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Moisture Associated Skin Damage

What is moisture associated skin damage (MASD)?

MASD is the general term for skin erosion and inflammation caused by prolonged exposure to moisture and irritants, including urine, faeces, digestive secretions, mucus, saliva, perspiration, and wound exudate.¹. 

This exposure damages the skin’s natural barrier, which can lead to inflammation, maceration, pain and, in many cases, an increased risk of infection. 

There are four main types of MASD2,3 these are:  

  • Incontinence associated dermatitis (IAD): due to moisture from urine and/or faeces exposure.
  • Peristomal moisture associated dermatitis: occurring around stomas where effluent or moisture leaks. 
  • Intertriginous dermatitis (ITD) or intertrigo: caused by friction and moisture between skin folds.
  • Periwound MASD: due to wound exudate overflowing onto surrounding skin.  

The development of MASD is not caused by moisture alone, and can often be exacerbated by: 

  • Enzymes, drug metabolites, and ammonia in bodily fluids. 
  • Altered skin pH due to ageing or incontinence. 
  • Presence of microbial flora, which can contribute to inflammation and secondary infection. 
  • Mechanical stress, including friction and shear from movement or personal care routines1,4. 

Populations at risk 
Individuals with incontinence, reduced mobility, obesity, or chronic wounds are particularly vulnerable to MASD. Individuals at higher risk may also struggle to maintain skin hygiene, increasing the risk of breakdown and infection presentations5. 

Assessment of different skin tones 
It’s important to note that MASD can present differently in people with dark skin tones, which can cause a delay in diagnosis and appropriate management6. 

For patients with more pigmented skin, traditionally recognised signs such as erythema, or “redness”, can be more difficult to spot. Looking for more subtle colour changes or hyperpigmentation, changes to skin texture, and taking note of patient-reported symptoms6 can help detect moisture damage earlier.  

The importance of recognising MASD early 
When left untreated, MASD can progress rapidly and lead to serious complications including infection, delayed wound healing, and secondary pressure damage. Early recognition and appropriate management can help minimise discomfort and improve outcomes7. 

Flaminal®: Advanced treatment for moderate to severe MASD
Flaminal® is an enzyme alginogel designed to support skin healing in wounds, including moisture damage, without harming healthy skin cells8. 

How Flaminal® Hydro and Flaminal® Forte support MASD management ?
Flaminal® is indicated in the treatment for moderate to severe MASD9,10 and provides effective management for MASD, with benefits that include: 

-Broad spectrum antimicrobial protection10, including protection against Candida albicans  
-Supports antimicrobial stewardship (AMS), with no recorded antimicrobial resistance to date10,11. 
-Exudate management: the absorbent alginate matrix within Flaminal® absorbs excess exudate8. 
-Promotes autolytic debridement, helping to gently remove slough and debris8. 
-Versatile for MASD of all aetiologies, and for various wound healing challenges9. 
-Comfortable for patients, allowing for atraumatic dressing changes even in painful, sensitive areas9. 
-Easy to apply even to difficult-to-dress areas, making it ideal for shared care and for use across different treatment settings. 

 

References  

  1. Gray M, Black JM, Baharestani MM, et al. Moisture-associated skin damage: overview and pathophysiology. Journal of Wound, Ostomy and Continence Nursing. 2011;38(3):233–241. 
    https://pubmed.ncbi.nlm.nih.gov/21659845/ 

  1. Harte K, Marshall K. Recognising MASD in diverse skin tones. Wounds UK. 2025;21(1). (In press) 

  1. Beele H, Call E, Cowdell F, et al. Best Practice Principles: Skin care for the older person. Wounds International. 

  1. Dhoonmoon L, Hooper J, Searle R. Moisture-associated skin damage made easy. Wounds UK. 2023;19(1). 

  1. Prevention and care for moisture-associated skin damage: A scoping review. Tissue Viability Society. 2024. 
    https://pubmed.ncbi.nlm.nih.gov/38906753/ 

  1. Dhoonmoon L. Skin tone in the management of incontinence-associated dermatitis. 
    Urology & Continence Care Today, January 2026. 

  1. Beldon P. Prevention and management of moisture-associated skin damage. British Journal of Nursing. 2018;27(6):S28–S34. 

  1. White R, Cutting KF. Flaminal®: Alginate hydrogel with antimicrobial enzyme system. British Journal of Nursing. 2006;15(11):S24–S28. 

  1. Davies P. The use of enzyme alginogel Flaminal® in MASD. Journal of Community Nursing. 2021;35(4):58–62. 

  1. Wounds UK. Time for an update: the versatility of Flaminal demonstrated in a large-scale clinical evaluation. Wounds UK. 2023;19(3):70–76. 

  1. White R. Flaminal®: a novel approach to wound bioburden control. Wounds UK. 2006;2(3):64–69. 

MASD, particularly moderate to severe MASD, is associated with a range of complications and can significantly affect a patient’s quality of life. The effective management of moisture damage, through appropriate wound care and addressing the underlying source of moisture, can both reduce the risk of infection and further skin damage and support improved healing outcomes for patients. 

Flaminal® Hydro/Forte

Flaminal® supports the natural healing of acute and chronic wounds.